Oncofertility Publications - Human Follicle Culture
Building off our work in the mouse and nonhuman primate models, we recently showed that we can grow human secondary follicles in the alginate hydrogel-based follicle culture system. Early secondary follicles, isolated from ovarian tissues from human cancer patients, grew to the antral stage after thirty days in culture. These follicles produced hormones, had intact somatic cell-oocyte architecture, and contained oocytes that appeared to have nuclear competence. This breakthrough highlights the huge potential of translating bench science into clinical practice for fertility preservation.
Did you know that cancer treatments can affect the fertility of men, women, and children? Fertility preservation methods are most effective when used before cancer treatments begin.
For information about fertility preservation or to get a referral to a fertilty preservation center near you, please call the FERTLINE! This resource is available to patients, families and health care professionals.
If you are a researcher, explore the following pages to find out more about the Oncofertility Consortium’s research endeavors, access up-to-date Oncofertility-related techniques and protocols, browse our most recent publications, and search our media archives